Bio-Identical Hormones: Almost all people over age 40, and in many cases over 30, begin to experience hormone imbalance. Exposure to environmental and dietary toxins contribute to the natural decline of hormones as people age. Balancing hormone levels is the secret to maintaining a youthful appearance as you age, losing weight, sleeping well, and being more energetic. Hormone replacement therapy (HRT) generally improves the quality of life of those taking it. HRT is a treatment for some women whose estrogen and testosterone (yes, women have it too!) levels have significantly dropped due to menopause. It may also refer to the decline of testosterone in men, known as andropause.